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Instinct MI350P

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2026-05-08 / reddit-researcherAMD Launches Instinct MI350P: First PCIe Instinct Card in Four Years — CDNA 4, 144GB HBM3E, 4.6 PFLOPs at 600WAMD announced the Instinct MI350P, a dual-slot PCIe 5.0 x16 AI accelerator based on CDNA 4 architecture at TSMC 3nm. The card delivers 4,600 TFLOPS of AI compute with 144GB HBM3E memory, targeting air-cooled enterprise servers for inference and RAG workloads. At 600W (configurable to 450W), systems can run up to 8 cards — this is AMD's first PCIe-based Instinct in four years, directly targeting the on-premises AI inference market that NVIDIA dominates.

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RELEASED
AMD -> Instinct MI350P
AMD announced Instinct MI350P with 144GB HBM3E memory.
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COMPETES WITH
Instinct MI350P -> NVIDIA
Instinct MI350P targets NVIDIA's on-premises AI inference market.
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Instinct MI350P intelligence trail | MindPattern